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課程名稱 |
分子遺傳學
Molecular Genetics |
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開課學期 |
104-2 |
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授課對象 |
生物資源暨農學院 作物科學組 |
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授課教師 |
林彥蓉 |
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課號 |
Agron5075 |
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課程識別碼 |
621 U5300 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期一7,8,9(14:20~17:20) |
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上課地點 |
農藝112 |
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備註 |
與黃永芬、張俊哲合開
總人數上限：30人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1042Agron5075_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
WEEK CONTENTS
1 Introduction to Molecular Genetics
2 The structure and function of DNA
3 The structure and function of chromosome
4 DNA replication
5 Repair of DNA double-strand breaks and homologous recombination
6 MIDTERM I
7 Transcription in prokaryotes
8 Transcription in eukaryotes
9 RNA processing
10 The mechanism of translation
11 Gene regulation in development
12 MIDTERM II
13 Mobile DNA
14 Tools and techniques in molecular genetics
15 Genomics
16 Genetic variation
17 FINAL
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課程目標 |
Molecular Genetics is the modern form of Genetics that studies the structure and function of genes at a molecular level. This field includes how genetic information is organized, replicated, expressed, regulated, and transferred from generation to generation. Topics of this course cover important issues from genes to genome and from proteins to proteome (details please see contents in the Syllabus). Concepts and applications of genome analysis and systems biology are also included. |
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課程要求 |
None |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
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指定閱讀 |
待補 |
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參考書目 |
I. Watson JD, Baker TA, Bell SP, Gann A, Levin M, and Losick R. (2008) Molecular Biology of the Gene 6th edition. Cold Spring Harbor Laboratory Press. (偉明)
II. Allison LA “Fundamental Molecular Biology” Blackwell Publishing. 2007 (合記)
III. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Peter Walter. (2009) Molecular Biology of the Cell 5th edition. Garland Science.
注意：NCBI 已免費提供第四版 (4th edition) 下載服務 (http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mboc4);第五版已於 2009 年出版，不過還未上線。
IV. 世界第一簡單分子生物學 (作者：武村政春; 譯者：連程翔; 出版社：世茂; 審訂：張俊哲)
本書為深入淺出，提供分生基本全貌之絕佳書籍！
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
2/22 |
Introduction to Molecular Genetics -- Lin |
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第2週 |
2/29 |
Holliday, 和平紀念日遇例假日補假 |
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第3週 |
3/07 |
The structure of DNA --Huang |
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第4週 |
3/14 |
Chromosome structure and function -- Huang |
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第5週 |
3/21 |
DNA replication -- Huang |
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第6週 |
3/28 |
DNA repair -- Huang |
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第7週 |
4/04 |
Holliday, 民族掃墓節 |
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第8週 |
4/11 |
Repair of DNA double-strand breaks and homologous recombination -- Huang |
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第9週 |
4/18 |
Midterm I -- Huang
Transcription in prokaryotes -- Lin
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第10週 |
4/25 |
Transcription in eukaryotes Lin |
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第11週 |
5/02 |
RNA processing -- Chang |
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第12週 |
5/09 |
The mechanism of translation -- Chang |
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第13週 |
5/16 |
Gene regulation in development -- Chang |
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第14週 |
5/23 |
Mobile DNA -- Lin |
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第15週 |
5/30 |
Midterm II -- Lin/Chang |
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第16週 |
6/06 |
Tools and techniques in molecular genetics -- Lin |
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第17週 |
6/13 |
Genome & Genetic variation -- Lin |
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第18週 |
6/20 |
Final -- Lin |
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